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- A novel decision support aid tool (DST) for optimal levothyroxine dosage after thyroidectomy

About the technology

Levothyroxine is a necessary synthetic hormone after removal of the thyroid gland, or in patients with an underactive tyroid gland. The optimal dosage varies between individuals, making several rounds of dose adjustments required. Due to long half-life of the hormone, it commonly takes 6-12 months for patients to finish their dose adjustment.

We have developed a decision support tool (DST) that calculates a dosage proposal for each individual patient. The invention shortens the time to arrive at the right medical dose for patients after surgery. This is acheived by repeatedly measuring the concentration of hormones in the blood for 2 weeks, and then using these data as input to a model, along with biodata. This new method can replace a long standing clinical practice with long intervals between dosage adjustments. The future goal is to adapt the model so it can also be used for all patients with all kinds of thyroid disorders.

Value proposition

  • 50% reduced time to correct dose
  • Patients quality of life improved
  • Can be performed at GPs office
  • High patient complience
  • Cost effective

Resources and partners

  • Clinically tested in a randomised multicentre study (Brun et al 2021. Intern. Federation for Medical and Biological Engineering Proceedings, Springer. 76:1264-1269)
  • Clinical validation studies ongoing
  • University Hospital of Northern Norway (UNN)
  • SINTEF
  • UiT The Arctic University of Norway
Image: With Thyroid Assist the time needed to achieve correct TSH levels is shortened significantly.

Opportunities for Collaboration

We are currently looking for industry partners or potential users who find interest in our technology. We are open for working together on the development of the DST to accommodate your needs.

Partners

Universitetet i Tromsø

Contact information

Foto: Marius Fiskum

Ingrid Skjæveland

Forretningsutvikler | Tech Transfer

ingrid@norinnova.no
Tlf. 991 57 143

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