- A novel decision support aid tool (DST) for optimal levothyroxinedosage after thyroidectomy
About the technology
Levothyroxine is a necessary synthetic hormone after removal of the thyroid gland, or in patients with an underactive thyroid gland. The optimal dosage varies between individuals, making several rounds of dose adjustments required. Due to long half-life of the hormone, it commonly takes 6-12 months for patients to finish their dose adjustment.
We have developed a decision support tool (DST) that calculates a dosage proposal for each individual patient. The invention shortens the time to arrive at the right medical dose for patients after surgery. This is acheived by repeatedly measuring the concentration of hormones in the blood for 2 weeks, and then using these data as input to a model, along with biodata. This new method can replace a long standing clinical practice with long intervals between dosage adjustments. The future goal is to adapt the model so it can also be used for all patients with all kinds of thyroid disorders.
Value proposition
- 50% reduced time to correct dose
- Patients’ quality of life improved
- Can be performed at GPs office
- High patient compliance
- Cost effective
Resources and partners
- Clinically tested in a randomized multicentre study (Brun et al 2021. Intern. Federation for Medical and Biological Engineering Proceedings, Springer. 76:1264-1269)
- Clinical validation studies ongoing
- University Hospital of Northern Norway (UNN)
- SINTEF
- UiT The Arctic University of Norway
Opportunities for Collaboration
We are currently looking for industry partners or potential users who find interest in our technology. We are open for working together on the development of the DST to accommodate your needs.
Partners
Contact information
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